Ehrenbolger K.*, Jespersen N.*, Sharma H.*, Sokolova Y.Y., Tokarev Y.S., Vossbrinck C.R., Barandun J.#, Differences in structure and hibernation mechanism highlight diversification of the microsporidian ribosome. PLoS Biology (2020) 18 (10), e3000958
Preprint at bioRxiv


Barandun J.#, Hunziker M., Vossbrinck C. R., and Klinge S., Evolutionary compaction and adaptation visualized by the structure of the dormant microsporidian ribosome. Nature Microbiology (2019), 4, p.1798–1804

M. Hunziker*, J. Barandun*#, O. Buzovetsky, C. Steckler, H. Molina, and S. Klinge#, Conformational switches control early maturation of the eukaryotic small ribosomal subunit. Elife (2019) vol. 8, pp. 1–16, Jun.


Sanghai Z. A.*, Miller L.*, Molloy K. R., Barandun J., Hunziker M., Chaker-Margot M., Wang J., Chait B. T. & Klinge S. Modular assembly of the nucleolar pre-60S ribosomal subunitNature (2018) 556:126–9.
Preprint at bioRxiv

Barandun J.*, Hunziker M.*, Klinge S. Assembly and structure of the SSU processome – a nucleolar precursor of the small ribosomal subunit. Current Opinion in Structural Biology (2018) Jan;49 85-93.


Barandun J.*, Chaker-Margot M.*, Hunziker M.*, Molloy K. R., Chait B. T. and S. Klinge. The complete structure of the small-subunit processomeNature Structural & Molecular Biology (2017) 24:944–53.
Preprint at bioRxivNews and Views

Barandun J., Damberger F. F., Delley C. L., J. Laederach, Allain F. H.-T., Weber-Ban E. Prokaryotic ubiquitin-like protein remains intrinsically disordered when covalently attached to proteasomal target proteins. BMC Structural Biology (2017) 17. 

Wang Y, Zhang R, Barandun J, Du H, Chen D, Jia Y, Song Y, Vossbrinck B, Li C, Zhou Z, Vossbrinck CR, Xiang H. Divergence of a Tandem Duplication of Manganese Superoxide Dismutase in Nosema bombycis. J. Eukaryot. Microbiol. (2017) 1–11.

Chaker-Margot M., Barandun J., Hunziker M., S. Klinge. Architecture of the yeast small subunit processomeScience (2017); 355:eaal1880.


Hunziker M.*, Barandun J.*, Petfalski E., Tan D., Molloy KR., Kim KH., Dunn-davies H., Shi Y., Chaker-margot M., Chait BT., Walz T., Tollervey D. & Klinge S. UtpA and UtpB chaperone nascent pre-ribosomal RNA and U3 snoRNA to initiate eukaryotic ribosome assembly. Nature Communications. (2016) 7, 12090.


Chaker-Margot M., Hunziker M., Barandun J., Dill B. D., Klinge S. Stage-specific assembly events of the 6-MDa small-subunit processome initiate eukaryotic ribosome biogenesis. Nature Structural & Molecular Biology. (2015) 22(11), 920–923


Flütsch A.*, Schroeder T.*, Barandun J.*, Ackermann R., Bühlmann M., GrütterM. G.,Specific targeting of human caspases using designed ankyrin repeat proteins, Biological Chemistry. (2014) 1431-6730.


Barandun J., Delley C. L., Ban N. & Weber-Ban E. Crystal structure of the complex between Prokaryotic Ubiquitin-like Protein Pup and its Ligase PafAJ. Am. Chem. Soc. (2013) 135: 6794–7.

Schroeder T.*, Barandun J.*, Flütsch A.*, Briand C., Mittl P. R. E., Grütter M. G. Specific Inhibition of Caspase-3 by a Competitive DARPin: Molecular Mimicry between Native and Designed Inhibitors. Structure (2013) 21, 277–89.


Barandun J., Delley C. L. & Weber-Ban E. The pupylation pathway and its role in mycobacteria. BMC biology (2012) 10, 95.

Özcelik D.*, Barandun J.*, Schmitz N., Sutter M., Guth E., Damberger F. F., Allain F. H.-T., Ban N., Weber-Ban E. Structures of Pup ligase PafA and depupylase Dop from the prokaryotic ubiquitin-like modification pathwayNature Communications (2012) 3, 1014.

* equal contribution
# corresponding author